When you think of a vaccine, they often imagine a long needle in a syringe in front of a slight pimple on their arm, and the days of pain continue as they recover.
University researchers from California, Riverside (UCR) have successfully attempted to deliver messenger RNA (mRNA) vaccine technology through edible plants.
They want to be able to grow vegetables capable of delivering vaccines with the same technology used to develop Pfizer with BioNTech. Modana COVID19 vaccine.
Plants are easier to digest than vaccines, and vaccines should be kept very cold to prevent rotting, making them easier to transport and store.
If successful, these plants could benefit low-income countries as they are easier to store and transport than the dose of Covid vaccine.
Researchers at the University of California at Riverside are developing a method of inserting mRNA into plant chloroplasts for oral administration of vaccines via edible vegetables (file photo).
The mRNA technology used in Pfizer and Moderna injections, and potentially in plants, has been around for a long time, but until recently it was rarely used in medicine.
It works by telling the body how to form peplomeric proteins that promote infection with Covid.
When the human immune system detects a protein, it fights it off and when it reappears in the human body due to exposure to the virus, it forms immunity against the protein.
Companies are currently working to apply this technology to other vaccines. Annual influenza vaccination.
Juan Pablo Giraldo (photo) is leading the study and says he believes “it can have a significant impact on people’s lives.”
“Ideally, a plant produces enough mRNA to vaccinate a person,” said Juan Pablo Giraldo, senior researcher and associate professor of botany and plant science at UCR. to augment. In the statement ..
“We are testing this approach with spinach and lettuce and have a long-term goal for people to grow it in their own backyards.
“Farmers also have the potential to eventually develop the entire sector. ”
Researchers believe that the chloroplasts in cells may carry genes that are not normally part of the plant.
This property means that this part of the plant has a lot of potential.
“These are small solar power plants that produce sugar and other molecules that allow plants to grow,” Giraldo explains.
“These are also undeveloped sources for making the desired molecules. ”
The team is working to find an ideal way to deploy on chloroplasts in a way that doesn’t destroy mRNA material.
If successful, you will be able to give the Covid vaccine and other vaccines using mRNA technology orally.
It also makes it much easier to transport vaccines over long distances.
Current mRNA vaccines should be stored at a low temperature of -130f (-90C) and dry ice should be used.
This can make the long-distance transport of vaccines difficult and expensive, and can hamper access to vaccines, especially in rural or remote areas of the United States.
Third world countries are also affected. Many people may not have the resources to transport and store the vaccines needed to distribute vaccines across the country.
Instead, plants can easily grow and be easily transported long distances or even overseas, using existing technology to distribute the products around the world.
“I’m very excited about all of this research,” Giraldo said.
“I think it can have a big impact on people’s lives. ”
Currently, in the United States, about 64% of the total population is vaccinated at least once with the COVID-19 vaccine, and 54% is fully vaccinated.
However, these numbers are much lower globally, with 44% of the world’s population vaccinated at least once and 32% fully vaccinated.
Scientists are working on the development of plants capable of providing mRNA vaccine technology Source link Scientists are working on developing plants capable of providing mRNA vaccine technology